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Managing Cystic Fibrosis-Related Diabetes

Posted on December 31, 2019January 5, 2020 by admin

Diabetes is very common in people with cystic fibrosis (cf). it most often occurs as they get older. people with cf and diabetes have a unique type of diabetes called cystic fibrosis–related diabetes (cfrd)*. one study found that up to % of adults with cf have some form of glucose intolerance and % have cfrd.. With diabetes do not convert food into fuel very well. they lose weight, lack energy, and can have other problems. diabetes is very common in people with cystic fibrosis (cf). it most often occurs as they get older. people with cf and diabetes have a unique type of diabetes called cystic fibrosis–related diabetes (cfrd).. Cystic fibrosis–related diabetes is a diagnosis different from type 1 and type 2 diabetes in pathophysiology, diagnosis, and management. sufficient evidence is present to support the benefits of glycemic control on lung function in patients with cystic fibrosis–related diabetes..

Cystic fibrosis-related diabetes (cfrd) is a unique type of diabetes that is common in people with cf. with early diagnosis and proper treatment, cfrd can be managed successfully.. Cystic fibrosis (cf) is the most common lethal genetic autosomal recessive disease in caucasians, with a worldwide prevalence of 1 in ~2500 live births. cystic fibrosis-related diabetes (cfrd) is the most common comorbidity in cf. there are important pathophysiologic dif-ferences between cfrd and type 1 and type 2 diabetes (table 1),. Cystic fibrosis–related diabetes (cfrd) is the most common comorbidity in people with cystic fibrosis (cf), occurring in ∼20% of adolescents and 40–50% of adults (1). while it shares features of type 1 and type 2 diabetes, cfrd is a distinct clinical entity..

Resources - Johns Hopkins Cystic Fibrosis Center

Management of cystic fibrosis–related diabetes in children and adolescents these consensus guidelines published in 2018 outline the diagnostic criteria, pathophysiology, clinical features, survival, prognosis and screening of cystic fibrosis as well as treatment approaches of diabetes in patients with cystic fibrosis.. Cystic fibrosis–related diabetes is associated with a 6-fold higher mortality rate compared with those with cf alone. the management of cfrd adds a further burden for the patient and creates new therapeutic challenges for the clinical team.. Cystic fibrosis-related diabetes (cfrd) in the 1950s, cf patients had a life expectancy of less than a year. by 1970, it was 8 years. this low life span was multifactorial, but mostly attributable to poor management of pulmonary infections and to a lack of understanding of the defect in cf..

Cystic fibrosis–related diabetes is associated with a 6-fold higher mortality rate compared with those with cf alone. the management of cfrd adds a further burden for the patient and creates new therapeutic challenges for the clinical team.. With diabetes do not convert food into fuel very well. they lose weight, lack energy, and can have other problems. diabetes is very common in people with cystic fibrosis (cf). it most often occurs as they get older. people with cf and diabetes have a unique type of diabetes called cystic fibrosis–related diabetes (cfrd).. Cystic fibrosis–related diabetes (cfrd) is the most common comorbidity in people with cystic fibrosis (cf), occurring in ∼20% of adolescents and 40–50% of adults (1). while it shares features of type 1 and type 2 diabetes, cfrd is a distinct clinical entity..

Reference

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